منابع مشابه
Today ' s Treatment Use of antibiotics Penicillins
Penicillins are among the most frequently prescribed drugs, and the 15 different members are marketed in many forms and combinations. I will try to place the use of both the older ones and also the more recent additions. In both clinical usage and antibacterial activity there are four main divisions of the penicillin family-benzylpenicillin (and other closely related antibiotics), the penicilli...
متن کاملBiosynthesis of penicillins; new crystalline biosynthetic penicillins.
Paper III (1) in this series describes several tests which were found to be useful in determining whether a given compound is utilized by the mold in penicillin formation. To provide proof of the incorporation of various acyl groups into the penicillin molecule and to be able to determine the chemical characteristics and biological properties of the various penicillins, isolation and crystalliz...
متن کاملToxicity of the Penicillins.
THE absence of direct toxicity is one of the most remarkable properties of the penicillin molecule; that is to say, the penicillin molecule as we know it and as we should use it. If you try hard enough, you can make it toxic by altering it or abusing it, as I shall try to show later. With this reservation, one can say that penicillin G and the main therapeutic derivatives of 6-aminopenicillanic...
متن کاملThe New Penicillins in Endocarditis.
FEW infections can kill a human being as rapidly as acute staphylococcal endocarditis in its most fulminant form. Infections caused by penicillinase producing staphylococci have been particularly difficult to manage. Successful treatment has been 'accomplished by combinations of antibiotics, by vancomycin, and even by huge doses of penicillin G. Still, the problem of therapy remains formidable....
متن کاملAntibacterial activity of the penicillins.
Penicillin, the first antibiotic of clinical importance to be discovered, is in many ways the best. Against most pathogenic species of Gram-positive bacteria and Gramnegative cocci a concentration of 0.02 ptg./ml.t or less inhibits growth and a concentration not much higher is actively bactericidal. Moreover, apart from hypersensitivity reactions, penicillin is probably the least toxic of the a...
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ژورنال
عنوان ژورنال: BMJ
سال: 1990
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.300.6735.1289